Search on: APC10 SUBUNIT, ANAPHASE-PROMOTING COMPLEX-CYCLOSOME 
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Descriptor English:   Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome 
Descriptor Spanish:   Subunidad Apc10 del Ciclosoma-Complejo Promotor de la Anafase 
Descriptor Portuguese:   Subunidade Apc10 do Ciclossomo-Complexo Promotor de Anáfase 
Tree Number:   D08.811.464.938.750.092.625
D12.776.167.024.625
Definition English:   Apc10 is necessary for coactivator-dependent substrate recognition by the anaphase-promoting complex-cyclosome. It binds the Apc2 subunit, which is a part of the catalytic core, and interacts with coactivators Cdh1 or Cdc20 to recruit substrates to the complex. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55274 
Unique Identifier:   D064197 

Occurrence in VHL:
 

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